It's a dangerous road attempting a well loved classic, most remakes flourish when the original's shadow has long faded. There will be another Wizard of Oz, a few Snow White interpretations, numerous Vampire spinoffs, and invariably a flood of zombie pictures (Walking Dead, World War Z, Pride and Prejudice and Zombies...). The more that people feel out of control, the greater the need for a way to escape.
If Hollywood wanted to attempt a comic/anime translation, why not veer toward the lesser known? Darker than Black, Mushi-shi, Baccano!, Fullmetal Alchemist, or Samurai Champloo all have in-depth story lines (Not to mention some of them do not feature Japanese protagonists). Taking a cue from the break out success of Game of Thrones there is the impeccable twin novel epic adventure by Guy Gavriel Kay, The Sarantine Mosaic. Or perhaps the lesser Disney spun tales such as Rumpelstiltskin or even Robert Munsch's Paper Bag Princess? For now, we'll have to be content with board games ... wholly original storyline and famous in name only.